<html><head><meta http-equiv="Content-Type" content="text/html charset=windows-1252"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;">Hi everyone,<div><br></div><div>… the PhD project presentations by our colleagues in Maths / Computational Biology might be of interest to some of you. If you are interested in this kind of stuff, you can subscribe to the CMMB mailing list (info below) and also check out their google calendar:</div><div><br></div><div><div><a href="http://tinyurl.com/p97jopd">http://tinyurl.com/p97jopd</a></div><div><br></div><div>Best,</div><div>Denis</div><div><br></div><div>----------------------------------------------------------</div><div><br></div><div><div apple-content-edited="true"><div style="orphans: 2; text-align: -webkit-auto; widows: 2; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div style="text-align: -webkit-auto; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;"><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">Dear All, </span></div><div><br></div><div style="orphans: auto; widows: auto;"><font face="Arial, sans-serif" size="2"><span style="white-space: pre-wrap;">next Tuesday we will have four back-to-back talks by Agne Tilunaite, Áine Byrne, Alban Levy and Aytul Gokçe, who will discuss their PhD projects (see details below). I propose to have lunch altogether in the common room around 12 noon: It would be a good opportunity to catch up.</span></font><span style="font-family: Arial, sans-serif; font-size: small; text-align: -webkit-auto; white-space: pre-wrap;"> </span></div><div style="orphans: auto; widows: auto;"><font face="Arial, sans-serif" size="2"><span style="white-space: pre-wrap;"><br></span></font></div><div style="orphans: auto; widows: auto;"><font face="Arial, sans-serif" size="2"><span style="white-space: pre-wrap;">—Daniele</span></font></div><div style="orphans: auto; widows: auto;"><font face="Arial, sans-serif" size="2"><span style="white-space: pre-wrap;"><br></span></font></div><div style="orphans: auto; widows: auto;"><font face="Arial, sans-serif" size="2"><span style="white-space: pre-wrap;">------------------------------------------------------------------------------</span></font></div><div style="orphans: auto; widows: auto;"><b class="">Date and venue</b>:<br class="">Tue, 11/11/14, 14:00 – 15:00 in UP-PHYS-B13+</div><div style="orphans: auto; widows: auto;"><br></div><div style="orphans: auto; widows: auto;"><span style="font-family: Arial, sans-serif; font-size: small; white-space: pre-wrap;">------------------------------------------------------------------------------</span></div><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Speaker</b>: </span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Agne Tilunaite</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Title</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Modelling of intracellular calcium dynamics
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Abstract</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Calcium is a universal second messenger that transmits information through spike train patterning. It is assumed that these patterns depends on the stimulus. Thus, we aim to predict the cell response to a given external stimulations. In our analysis we investigate the factors determining the cellular response, such as the calcium spiking rate. In this talk I will give a short introduction how Gaussian processes can be used to estimate the time- dependent rate of calcium spikes.<br></span></div><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><br></span></div><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">------------------------------------------------------------------------------</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">
</span><b style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Speaker</b><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: </span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Áine Byrne</span></div><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Title</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Next generation neural mass models: rate and coherence
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Abstract</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Many popular neural mass models for describing cortical population dynamics, such as Wilson-Cowan or Jansen-Rit, track an average activity without recourse to describing the degree of synchronisation or coherence within a population. This could of course be tracked within a large-scale model of synaptically interacting conductance based neurons, though at the expense of analytically tractability. Thus it is of interest to seek levels of description that provide a bridge between microscopic single neuron dynamics and coarse grained neural mass models, though preserving some notion of within-populati</span><wbr style="font-family: Arial, sans-serif; orphans: auto; white-space: pre-wrap; widows: auto;"><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">on coherence. For a theta neuron choice of microscopic dynamics we can make use of recent results by Luke et al. [Complete Classification of the Macroscopic Behavior of a Heterogeneous Network of Theta Neurons, Neural Computation 25, 3207–3234 (2013)] to evolve a mean field variable that captures both rate and coherence. We generalise their approach to account for realistic synaptic dynamics within an excitatory-inhi</span><wbr style="font-family: Arial, sans-serif; orphans: auto; white-space: pre-wrap; widows: auto;"><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">bitory network structure, and analyse the model using bifurcation analysis and linear response theory. Future work will involve collaboration with colleagues in the Sir Peter Mansfield Magnetic Resonance Centre at Nottingham to use this new framework to understand the generation of beta-rhythms seen in motor cortex, and deliver the first suitable model for understanding so-called beta-rebound. This is readily observed in MEG recordings whereby hand movement causes a drop in the beta power band attributed to a loss of network synchrony.</span></div><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><br></span></div><div><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">------------------------------------------------------------------------------</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">
</span><b style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Speaker</b><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: </span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Alban Levy</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Title</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Data mining exploration of cochlear nucleus' cells
Abstract: We use data mining tools to explore neuronal data - more precisely, spike trains extracted from a cat's cochlear nucleus - in order to try to understand their neural code.
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</span><b style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Speaker</b><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: </span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto;">Aytul Gokçe</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Title</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Spiral Waves : Interface Analysis in a Neural Field
</span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);"><b>Abstract</b></span><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">: Spiral waves are stationary (self-sustained</span><wbr style="font-family: Arial, sans-serif; orphans: auto; white-space: pre-wrap; widows: auto;"><span style="font-family: Arial, sans-serif; font-size: small; orphans: auto; white-space: pre-wrap; widows: auto; background-color: rgb(255, 255, 255);">) rotating travelling waves that have been observed in many chemical and biological systems. In this talk, I will first provide a neural field model to create robust spiral waves that settle in 2D excitable media, and then I will describe the activity patterns using dimensionally reduced equations, leading to the interface between low and high activity states of neural activity.</span></div><div><br></div></div></div></div></div></div></div></div><br class="Apple-interchange-newline"></div><br class="Apple-interchange-newline"></div><br class="Apple-interchange-newline"><br class="Apple-interchange-newline"></div><br>_______________________________________________<br>Maths-CMMB mailing list<br><a href="mailto:Maths-CMMB@lists.nottingham.ac.uk">Maths-CMMB@lists.nottingham.ac.uk</a><br><a href="http://lists.nottingham.ac.uk/mailman/listinfo/maths-cmmb">http://lists.nottingham.ac.uk/mailman/listinfo/maths-cmmb</a></div></div></body></html>